Tretinoin with Cas 302-79-4
Tretinoin Quick Details
- Chemical Name: Tretinoin
- CAS No.: 302-79-4
- EINECS: 206-129-0
- Molecular Fomula: C20H28O2
- Molecular weight: 300.44
- Appearance: Yellow or light orange crystalline powder
- Assay: 99%min
- Synonyms: 3,7-DIMETHYL-9-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-2E,4E,6E,8E-NONATETRAENOICACID; 3,7-DIMETHYL-9-(2,6,6-TRIMETHYL-1-CYCLOHEXEN-1-YL)-2Z,4E,6E,8E-NONATETRANENOICACID;(L)-ISOTRETINChemicalbookOIN; RETINOICACIDALLTRANSISOMER; VitaminAAcid,ATRA,Tretinoin; TRETINOIN,POWDER;TRETINOIN,POWDER,USP;(2E,4Z,6E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6-trienoicacid; Retinoic acid.
Tretinoin Description
What is Tretinoin?
Yellow or light orange crystalline powder with a similar odor to vitamin methyl acetate. Easy to dissolve in methanol, ethanol, acetone, chloroform, dichloromethane, and also soluble in vegetable oils and fats. Unstable under light and heat, absorbs moisture in the air, and aggregates and deteriorates when exposed to water. The melting point of all trans vitamin A acid is 180-182 ℃, and the melting point range when mixed with a small amount of isomers is 170-190 ℃. Retinoic acid is mainly used to treat psoriasis, ichthyosis, follicular keratosis, acne, lichen planus, verrucous epidermal nevi, subepithelial pustulosis, vitiligo, pityriasis hirsuta, and simple pityriasis on the face. In addition, it also has a certain preventive effect on skin cancer and other diseases.
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Tretinoin Typical Properties
| Item | Specification | Results |
| Appearance | Yellow or light orange crystalline powder | Conforms |
| Identification | The IR absorption spectrum should correspond with reference spectrum | Conforms |
| Identification | Should exbihits maximum absorption at 325nm | Conforms |
| Assay | 97.0-103.0% | 99.93% |
| Loss on drying | ≤0.5% | 0.03% |
| Ignition residue | ≤0.1% | 0.02% |
| Heavy matals | ≤0.002% | Conforms |
| Isotretinoin | ≤5% | 0.26% |
| Conclusion | The results conforms with USP43 standards | |
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Tretinoin Applications
- Used for abnormal acne, ichthyosis, and abnormal psoriasis
- Used as an anti keratotic drug.
- Used to treat various skin diseases such as multiple common warts and keratinization abnormalities, such as ichthyosis and follicular keratosis
Recommended Dosage:
Local external application
- Ointment: Apply 0.1% ointment topically to other keratinized acne lesions and 0.05% ointment topically to acne lesions. Used every night Clean the skin with warm water and apply the medicine once.
- Gel: Apply appropriate amount to the affected part. At the beginning of treatment, apply it every other day or every three days, and then apply it every night before going to bed.
Tretinoin Package&Storage
Package: 1kg/bag;25kg/drum
Storage: Store in a cool place and keep it sealed to avoid direct sunlight.
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