2-Deoxy-D-Ribose with CAS 533-67-5
2-Deoxy-D-Ribose Quick Details
- Chemical Name:2-Deoxy-D-Ribose
- CAS No.: 533-67-5
- EINECS: 208-573-0
- Molecular Formula: C5H10O4
- Molecular weight: 134.13
- Appearance: White to off-white powder
- Assay: 99%min
- Synonyms:D-.alpha.-Ribodesose;Deoxyribose;D-Ribose, 2-deoxy-;2-deoxy-d-erythro-pentos;2-Deoxypentose;2-Desoxy ribosoe;D-(-)-2-DEOXYRIBOSE;D-2-DEOXYRIBOSE
2-Deoxy-D-Ribose Description
What is 2-Deoxy-D-Ribose?
2-Deoxy-D-Ribose is a naturally occurring deoxy sugar (deoxypentose) derived from D-ribose, in which the hydroxyl group at the 2-carbon position is replaced by hydrogen. This structural modification makes it the sugar component of the DNA backbone (as opposed to ribose, which forms the RNA backbone), giving 2-Deoxy-D-Ribose fundamental importance in molecular biology and biochemistry.
Beyond its role in nucleic acid structure, 2-Deoxy-D-Ribose is also generated in the body as a metabolic breakdown product of thymidine, and research has shown it plays a role in promoting angiogenesis (new blood vessel formation) and supporting cellular energy metabolism.
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2-Deoxy-D-Ribose Typical Properties
| Item | Specification | Results |
| Appearance | White to off-white powder | Conforms |
| Solubility（5% aqueous
solution） |
Complete and clear | Conforms |
| PH | 6.0-8.0 | 6.8 |
| Moisture | <1.0% | 0.12% |
| Loss on drying | <0.5% | 0.1% |
| Specific Rotation | -54.0°～-58.0° | -56.4° |
| Heavy Metals | ≤20ppm | <10 ppm |
| Residue on ignition | ≤0.5% | 0.11% |
| Purity | ≥99.0% | 99.8% |
| Conclusion | The results conforms with enterprise standards | |
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2-Deoxy-D-Ribose Applications
1. Pharmaceutical & API Intermediate
2-Deoxy-D-Ribose is a key starting material and intermediate in the synthesis of nucleoside-based active pharmaceutical ingredients, including certain antiviral and anticancer drug candidates. Its role as the DNA sugar backbone makes it essential for nucleic acid chemistry and related organic synthesis.
2. Cosmetic & Skincare Active Ingredient
As a cosmetic raw material, 2-Deoxy-D-Ribose (and its parent compound D-ribose) is used in anti-aging and skin-repair formulations. Clinical research on topical ribose-based formulations has reported measurable improvements in skin elasticity, radiance, and wrinkle appearance after regular use, attributed to enhanced cellular ATP regeneration and fibroblast activity.
3. Hair Growth & Scalp Care Formulations
Preclinical studies have demonstrated that topical 2-Deoxy-D-Ribose gel can stimulate hair follicle regrowth in androgenetic alopecia models, showing efficacy comparable to established topical treatments in animal studies. This has made 2dDR an ingredient of interest for next-generation scalp and hair care products.
4. Wound Care & Regenerative Formulations
2-Deoxy-D-Ribose promotes angiogenesis and has been studied in topical wound-healing applications, including hydrogel dressings designed to accelerate tissue repair.
Recommended
Dosage: Actual usage should always be confirmed through your own stability and compatibility testing, and finished products must comply with the cosmetic/pharmaceutical regulations of your target market.
2-Deoxy-D-Ribose Package&Storage
- Package: 1kg/bag;25kg/drum
- Storage: Store in a cool place and keep it sealed to avoid direct sunlight.
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