Introduction(CAS 110-27-0)
Isopropyl Myristate (IPM) is a chemical raw material synthesized through the esterification of isopropanol and myristic acid. It appears as a colorless and transparent liquid with a slight characteristic odor. Due to its excellent emollient properties, IPM is widely used in the cosmetic and pharmaceutical industries, serving as a key ingredient in many formulations. Its ability to enhance texture, improve absorption, and provide a non-greasy feel makes it indispensable in numerous product applications. These qualities explain why IPM has become a crucial component in a variety of formulations across different sectors.
What is Isopropyl Myristate(CAS 110-27-0)
Chemical Identity
IPM is a saturated fatty acid ester, chemically known as isopropyl myristate(CAS No. 110-27-0), and the molecular formula is C₁₇H₃₄O₂. Key physical properties include a boiling point around 258°C, a density of approximately 0.85 g/cm³, and a refractive index near 1.43.
IPM is characterized by low viscosity, excellent lubricity, and a non-polar nature, making it highly compatible with oil-based ingredients. In formulations, IPM enhances the penetration of active ingredients through the skin barrier and significantly improves the sensory feel, providing a light, smooth, and non-greasy finish that is highly valued in cosmetic and pharmaceutical products.
Synthesis of Isopropyl Myristate(IPM)
Industrially produced, it is produced through an esterification reaction. The main raw materials include:
- Myristic acid: a C14 saturated fatty acid typically extracted from natural animal and plant oils (such as coconut oil and nutmeg oil).
- Isopropanol: a commonly used alcoholic solvent.
Through precise control of reaction conditions, Autech Industry ensures that IPM products possess extremely high purity, which is crucial for demanding cosmetic and pharmaceutical applications.
Key Physicochemical Properties
Light and Refreshing Feel: IPM has extremely low viscosity, which is the main reason why it is popular in high-end skincare products. Its spreading coefficient is very high, which means that only a very small amount is needed to quickly and evenly spread and disperse on the skin surface. Users will feel a dry and lightweight skin sensation, without the greasy feeling of traditional oil residue.
Superior Emollient Quality: IPM is an excellent noncomedogenic moisturizer. It can effectively soften and moisturize the skin, help repair the skin barrier, and avoid pore blockage problems that may be caused by heavy oils such as mineral oil.
High Solvent Capacity: As a non-polar solvent, IPM has strong solubility. It can efficiently dissolve many oil-soluble active ingredients that are difficult to dissolve in water or traditional oils, such as sunscreen, fat-soluble vitamins, and fragrances. This ensures that the formula remains clear and transparent in appearance and remains stable and uniform during long-term storage.
Stability and Safety: IPM has good oxidative stability under normal storage conditions and is not prone to spoilage, thereby extending the shelf life of the final product. In addition, it remains stable across a wide range of pH values (from acidic to weakly alkaline) and has excellent compatibility with most commonly used formula ingredients.
Functions and Advantages of Isopropyl Myristate(CAS 110-27-0)
Skin Penetration Enhancer
Isopropyl Myristate (IPM) plays a critical role as a penetration enhancer by facilitating the deeper absorption of active ingredients through the skin’s outer barrier. This function is especially valuable in pharmaceutical and cosmetic formulations where the effectiveness of treatments depends on delivering actives to targeted skin layers. By improving permeation, IPM can increase bioavailability and enhance the overall performance of topical products.
Emollient
As a high-quality emollient, Isopropyl Myristate softens and smooths the skin surface while providing lasting hydration. Unlike many oils, it leaves a non-greasy, lightweight finish that greatly improves the sensory experience of skincare and cosmetic products. Its ability to reduce surface roughness and maintain skin moisture balance makes it a preferred ingredient for lotions, creams, sunscreens, and makeup formulations.
Solvent
Isopropyl Myristate possesses excellent solvent properties, enabling it to dissolve a wide range of oil-soluble active compounds, such as vitamins, antioxidants, and essential oils. This capability is essential for creating stable and effective formulations, as it helps uniformly disperse active ingredients and prevent separation. Furthermore, its compatibility with other formulation components contributes to enhanced product stability over time.
Carrier
In formulations, Isopropyl Myristate frequently acts as a carrier or delivery vehicle for active substances within oil-based, alcoholic, or lipid-rich systems. It promotes even distribution of ingredients throughout the product, ensuring consistent efficacy and texture. This versatility allows formulators to tailor products to specific needs, whether for enhanced skin absorption, improved spreadability, or better product stability.
Industry Applications of IPM（CAS 110-27-0）
Personal Care Industry
Isopropyl Myristate (IPM) is widely used in the personal care sector as both an emollient and an emulsifier. It enhances the texture and spreadability of products, providing a smooth, non-greasy feel that is highly desirable in skincare formulations. Typical applications include moisturizers, lotions, sunscreens, and various cosmetic products, where IPM helps improve skin hydration and product stability.
Pharmaceutical and Formulation Industry
In pharmaceuticals, IPM serves as a vital drug delivery carrier and ointment base. It facilitates the penetration of active pharmaceutical ingredients across the skin, improving their therapeutic efficiency. Its role in enhancing drug absorption makes it a preferred component in topical creams, gels, and ointments aimed at targeted treatment.
Industrial Applications
Beyond personal care and pharmaceuticals, IPM is used in industrial applications as a lubricant and additive. It is incorporated into lubricating oils and plastic processing aids to improve flow properties and reduce friction. These applications benefit from IPM’s chemical stability and effective lubrication qualities.
Other Potential Fields
IPM also finds use as a fragrance solvent in the perfume industry due to its excellent dissolving ability for aromatic compounds. Additionally, with compliance with relevant safety standards, it may be used as a food additive, demonstrating its versatility across diverse sectors.
Quality Standards and Specifications of Isopropyl Myristate (IPM)
Isopropyl Myristate is available in three main grades: industrial, cosmetic, and pharmaceutical.
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Industrial Grade: Used mainly in metalworking, plastics, and chemical processes where the highest purity is not essential. This grade tolerates minor impurities and is cost-effective for non-medical uses.
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Cosmetic Grade: Tailored for skin and personal care products, this grade meets specific safety and performance standards. It offers high purity suitable for moisturizers, lotions, and makeup products, ensuring safety and skin compatibility.
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Pharmaceutical Grade: The highest purity level, this grade complies with strict regulatory standards for medical and therapeutic applications. It is used in topical creams, ointments, and drug delivery systems, valued for being non-toxic and hypoallergenic.
Common Testing Parameters:
Key quality indicators for IPM include a purity of at least 98%, a low acid value to ensure minimal free fatty acids, a controlled saponification value, and minimal moisture content to maintain stability and effectiveness.
Packaging and Storage Recommendations:
IPM should be stored in tightly sealed containers away from light and heat exposure. Optimal storage conditions are in a cool, dry, and well-ventilated place to prevent oxidation and hydrolysis, thereby preserving product integrity and extending shelf life.
Why Choose AUTECH INDUSTRY as Your IPM（CAS 110-27-0）Supplier
Stable Supply Chain and Strict Quality Control
Autech Industry ensures a reliable, continuous supply of Isopropyl Myristate (IPM) through a well-managed supply chain and rigorous quality control processes. This guarantees product consistency and high purity to meet diverse industrial needs.
Multiple Purity Grades Available
We offer IPM in various grades, including industrial, cosmetic, and pharmaceutical, catering to the specific requirements of each industry and application, ensuring compliance with relevant standards.
Extensive International Export Experience
With established export capabilities, Autech Industry successfully serves clients across Europe, America, and Asia. Our global market insight ensures smooth logistics and regulatory compliance.
Flexible Packaging and Fast Delivery
Customized packaging options and efficient order processing allow us to provide quick turnaround times and meet bulk purchasing demands, making us a dependable partner for large-scale procurement.
Conclusion
Isopropyl Myristate (IPM) is a highly versatile ingredient widely recognized across multiple industries for its exceptional emollient, solvent, and penetration-enhancing properties. As a key raw material in cosmetics, pharmaceuticals, and industrial applications, IPM plays a crucial role in improving product performance and user experience.
Autech Industry stands out as a reliable supplier of high-quality IPM, offering multiple purity grades to meet diverse industry standards. With a stable supply chain, stringent quality control, and extensive international export experience, Autech Industry is well-equipped to support your bulk IPM needs efficiently and flexibly.
