Alpha Lipoic Acid with Cas 1077-28-7
Alpha Lipoic Acid Quick Details
- Chemical Name:Alpha Lipoic Acid
- CAS No.: 1077-28-7
- EINECS: 214-071-2
- Molecular Fomula:C8H14O2S2
- Molecular weight:206.33
- Appearance:Slightly yellow crystal powder
- Assay: 99%
- Synonyms:Hydroxypropyl Cyclodextrin;Thioctic Acid(α-Lipoic Acid）;(1)-ALPHA-LIPOIC ACID;DL-α-Lipoic acid ;5-(1,2)Dithiolan-3-yl-pentanoic acid for synthesis;TIMTEC-BB SBB003484;THIOOCTIC ACID;dl-1,2-Dithiolane3-valericacid;DL-6-Thioctic acid
Alpha Lipoic Acid Description
What is Alpha Lipoic Acid?
Alpha Lipoic acid, also known as alpha lipoic acid (ALA), is an excellent natural antioxidant ingredient with the ability to scavenge free radicals. Its ability to scavenge free radicals is more than a hundred times that of vitamin C, making it particularly suitable for anti-aging products. The appearance of alpha lipoic acid is light yellow powdery crystals, almost odorless. Alpha lipoic acid is insoluble in water but soluble in fat solvents, and some classify it as a fat soluble vitamin; Easy to dissolve in methanol, ethanol, chloroform, and ether.
Alpha Lipoic acid has strong antioxidant capacity, which can remove active oxygen components that cause skin aging. Due to its smaller molecule size than vitamin E and its water and fat solubility, it is well absorbed.Alpha Lipoic acid is a vitamin like endogenous disulfide compound in the human body that can regenerate endogenous antioxidants. It exists in mitochondria and can eliminate free radicals that accelerate aging and cause disease.
Alpha Lipoic acid ,known as the “universal antioxidant”. It is absorbed through the intestine and enters cells in the body. It has the characteristics of both lipid solubility and water solubility, can travel throughout the body without obstruction, reaching any cellular site and providing comprehensive efficacy to the human body.
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Alpha Lipoic Acid Typical Properties
| Item | Specification | Results |
| Appearance | Slightly yellow crystal powder | Conforms |
| Purity | 99.0%-101.0% | 99.93% |
| Identification | A：The retention time of the major peak
of the Sample solution corresponds to that of the standard solution B：IR spectra of sample compares qualitatively to the IR spectra of the standard |
Conforms
Conforms
|
| Melting point | 60-62℃ | 61-62℃r |
| Loss on drying | ≤0.2% | 0.06% |
| Residue on Ignition | ≤0.1% | 0.02% |
| Specific rotation | -1.0° to +1.0° | 0° |
| Related substances
Single Impurity Total Impurities |
≤0.1% ≤2.0% |
0.01% 0.01% |
| Limit of polymer content | ≤2.0% | Conforms |
| Residual Solvents
Cyclohexane Ethyl Acetate Toluene |
≤3880ppm ≤500ppm ≤20ppm |
1060ppm 55ppm Not detected |
| Particle size | 100% through 40 mesh | conforms |
| Heavy metals | ≤10ppm | ＜10ppm |
| Cadmium | ≤1ppm | 0.052ppm |
| Arsenic | ≤1ppm | ＜0.01ppm |
| Lead | ≤3ppm | ＜0.02ppm |
| Mercury | ≤0.1ppm | ＜0.005ppm |
| Total Aerobic Microbial Count | ≤1000CFU/g | ＜100CFU/g |
| Yeast & Mold | ≤100CFU/g | ＜10CFU/g |
| E.Coli | Absence/g | Not Detectable |
| Salmonella | Absence/g | Not Detectable |
| Staphylococcus Aureus | Absence/g | Not Detectable |
| Conclusion | The results conforms with USP 43 standards | |
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Alpha Lipoic Acid Applications
Alpha lipoic acid (ALA) is mainly used to treat mild to moderate brain dysfunction caused by diabetes peripheral neuropathy, alcoholic neuropathy and ischemic cerebrovascular disease. Its core functions include:
Lowering blood sugar and blood lipids:
Reduce hepatic glucose output by inhibiting hepatic glucose-6-phosphatase activity; Promote the synthesis of very low-density lipoprotein, accelerate low-density lipoprotein metabolism, thereby reducing total cholesterol and low-density lipoprotein cholesterol content.
Antioxidant and anti-inflammatory properties:
Eliminate free radicals in the body to prevent cell damage; Blocking the conversion of arachidonic acid into prostaglandin E2 and exerting anti-inflammatory effects.
Improve microcirculation and energy metabolism:
Inhibit platelet adhesion and aggregation, improve microcirculation disorders such as angina pectoris and cerebral infarction; Promote mitochondrial energy synthesis and participate in energy metabolism.
Recommended
Dosage:exact dosage should be subject to customer’s finial product formulation
Alpha Lipoic Acid Package&Storage
- Package: 1kg/bag;25kg/drum
- Storage: Store in a cool place and keep it sealed to avoid direct sunlight.
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